mog peptide 35-55 MOG Peptide 35-55 - Mogcfa emulsion MOG Peptide Unraveling the Significance of MOG Peptide 35-55 in Neurological Research

Anaspecmog The MOG peptide 35-55 is a critical fragment of Myelin Oligodendrocyte Glycoprotein (MOG), a protein predominantly found in the central nervous system (CNS) and a key component of the myelin sheath.2024年5月31日—OM-MOG35-55 suppresses antigen-specific T cell responses associated with autoimmune demyelination. Based on these results, we developed different types of ... This specific peptide, spanning amino acids 35 to 55, has emerged as an indispensable tool in the research of demyelinating diseases, most notably multiple sclerosis (MS). Its ability to induce experimental autoimmune encephalomyelitis (EAE) in animal models makes it a valuable antigen for studying the mechanisms behind autoimmune attacks on myelin.

MOG (35-55) is recognized as an immunodominant epitope, meaning it elicits a strong immune response. When used as an antigen or immunogen, this MOG peptide fragment can trigger the production of anti-MOG antibodiesAnti MOG Syndrome- Symptoms, Diagnosis, Treatment. This process is crucial for researchers seeking to understand how the immune system mistakenly targets and damages myelinMOG (35-55) | Myelin Oligodendrocyte Glycoprotein. The resulting neurological disease in animal models often mirrors the relapsing-remitting pattern and plaque-like demyelination observed in human MSMOG (35-55) (2568) by Tocris, Part of Bio-Techne. This makes the MOG 35-55 peptide an excellent model for investigating the pathological processes involved in such conditions.MOG (35-55) TFA (Myelin Oligodendrocyte Glycoprotein ...

The sequence of the MOG peptide 35-55 is MEVGWYRPPFSRVVHLYRNGK.Myelin Oligodendrocyte Glycoprotein Peptide (35-55) ... This specific amino acid sequence is recognized by T cells, initiating an inflammatory cascade that leads to demyelination.Multiple Sclerosis Peptide – MOG (35-55) rat/mouse Studies have shown that immunizing mice, such as the C57BL/6 strain, with this MOG peptide can reliably induce EAE.MOG peptide (35-55) amide The resulting MOG induced EAE exhibits characteristics similar to MS, providing a platform for evaluating potential therapeutic interventions. Researchers often utilize high-purity MOG 35-55 peptide for these assays, ensuring reliable and reproducible results in T cell studies.

Beyond its role in inducing EAE, the MOG (35-55) fragment is also studied for its potential to suppress antigen-specific T cell responses associated with autoimmune demyelination. This suggests a complex interplay where the MOG peptide can both initiate and potentially modulate immune responses, opening avenues for novel therapeutic strategies. The MOG protein 35-55 is therefore a focal point for understanding the intricate mechanisms of autoimmune neurological disordersMOG (35-55) (mouse, rat) (trifluoroacetate salt).

Sourcing high-quality MOG 35-55 peptide is paramount for accurate research. Various suppliers offer this peptide in different forms, including trifluoroacetate salt and amide forms, with purity levels often exceeding 95% as determined by HPLCMOG (35-55) human – MEVGWYRPPFSRVVHLYRNGK. The molecular weight of the MOG(35-55) peptide is approximately 2582.00 g/molMOG (35-55) (2568) by Tocris, Part of Bio-Techne. It is typically stored at -20°C to maintain its stability and reactivity for research purposes. The availability of MOG peptide 35-55 for both mouse and rat models, as well as human variants, allows for comprehensive comparative studies.MOG Peptide 35-55Rat, Mouse... Читать далее →. Характеристики реактива. assay. ≥97% (HPLC). storage temp. −20°C ... Все характеристики. Facebook. Twitter.

The significance of the MOG peptide extends to understanding MOG antibody disease (MOGAD), a distinct neurological condition that shares some similarities with MS but is specifically characterized by antibodies targeting MOG. Research using the MOG 35-55 peptide helps differentiate between these conditions and explore the specific roles of MOG in various neurological pathologies.

In summary, the MOG peptide 35-55 is an indispensable research tool.MOG(35-55), Human_UA080263_斯达特公司官网 Its ability to model autoimmune demyelination through EAE induction, its role as a key epitope, and its potential implications in understanding conditions like multiple sclerosis and MOGAD underscore its importance in advancing neurological science. The study of this MOG peptide continues to shed light on the complex mechanisms underlying myelin damage and offers hope for the development of effective treatments for debilitating neurological diseases.